How physical training affects the cardiovascular system and the immune system in patients with metabolic syndrome. 

Cardiometabolic and immunological response to exercise training in patients with metabolic syndrome: retrospective analysis of two randomized clinical trials

In nearly one-third of German adults, multiple risk factors for diabetes and cardiovascular diseases coexist. These include a larger waist circumference, elevated blood pressure, and high blood lipid levels. This clustering of factors amplifies the risks more than any individual factor alone.

Collaborating with the Technical University of Munich, we examined who benefits most from structured training programs. Our findings revealed interactions between risk factors: for instance, individuals with very high triglycerides saw less improvement in blood pressure through exercise. In contrast, longer or more frequent training sessions yielded greater blood pressure reductions.

Future research at the Friede Springer Prevention Center will focus on optimizing combinations of exercise, diet, and medications to maximize individual outcomes. Interestingly, the molecule neuropilin-1, which showed significant improvement alongside triglyceride reductions, may offer therapeutic potential. Elevated blood pressure and blood lipid levels should always be managed by a doctor in accordance with current treatment guidelines!

Co-authors:
https://www.sport.mri.tum.de

Sponsored by:
https://dzhk.de
https://www.diabetesstiftung.de